I have no idea what happened. My game was working perfectly with Oblivion Reloaded and some other mods. But all of a sudden the next day it refuse to start. Whenever I create a new game or load a game, the game crashes on 15-25 percent on the loading bar. I removed all my plugins and OBSE files the game still crashes. I found out it was Oblivion Reloaded, so I disabled everything in Oblivion Reloaded to find what was teh issue and the game still crashes the exact same way. If I remove Oblivion Reloaded my game loads up normally. The only thing I have installed with Oblivion Reloaded is models, textures, and animations, could these cause an issue like this? I've tried both 6.5 and the latest Oblivion Reloaded, they both have this issue.
I have the requirements and I have STEAM overlay disabled.
OR doesn't cause un-passable crashes when properly installed. You've done something wrong. Uninstall everything, validate the game files via Steam, then reinstall OR per readme both in archive and here on this site. Let me know what happens.